Winners of Ghana Premier League; from 1956 to 2021.

The Ghana Premier League was officially formed in 1956 after the last Gold Coast Club Competition was held in 1953–54, the league is organized by the Ghana Football Association and was ranked as the 11th best league in Africa by the IFFHS from 2001–2010.

It has been dominated by Kumasi Asante Kotoko and Accra Hearts of Oak. The 3 bottom teams are relegated at the end of the season and placed in each zone of the Ghana Division One League.

The 2019/20 season was abrupted due to the Covid-19 pandemic that caused leagues across the globe to either go on hold or be cancelled.

Before the competition was renamed the Ghana Premier League in 1956, Accra Hearts of Oak won the competition from 1920 to 1956.

Below is a list of winners of the Ghana Premier League from 1920 to 2021:

• 1956: Hearts of Oak (Accra)
• 1957: no winner
• 1958: Hearts of Oak (Accra)
• 1959: Asante Kotoko (Kumasi)
• 1960: Eleven Wise (Sekondi-Takoradi)
• 1961–62: Hearts of Oak (Accra)
• 1962–63: Real Republicans (Accra)
• 1963–64: Asante Kotoko (Kumasi)
• 1964–65: Asante Kotoko (Kumasi)
• 1966: Mysterious Dwarves (Cape Coast)
• 1967: Asante Kotoko (Kumasi)
• 1968: Asante Kotoko (Kumasi)
• 1969: Asante Kotoko (Kumasi)
• 1970: Great Olympics (Accra)
• 1971: Hearts of Oak (Accra)
• 1972: Asante Kotoko (Kumasi)
• 1973: Hearts of Oak (Accra)
• 1974: Great Olympics (Accra)
• 1975: Asante Kotoko (Kumasi)
• 1976: Hearts of Oak (Accra)
• 1977: Sekondi Hasaacas (Sekondi)
• 1978: Hearts of Oak (Accra)
• 1979: Hearts of Oak (Accra)
• 1980: Asante Kotoko (Kumasi)
• 1981: Asante Kotoko (Kumasi)
• 1982: Asante Kotoko (Kumasi)
• 1983: Asante Kotoko (Kumasi)
• 1984: Hearts of Oak (Accra)
• 1985: Hearts of Oak (Accra)
• 1986: Asante Kotoko (Kumasi)
• 1987: Asante Kotoko (Kumasi)
• 1988–89: Asante Kotoko (Kumasi)
• 1989–90: Hearts of Oak (Accra)
• 1990–91: Asante Kotoko (Kumasi)
• 1991–92: Asante Kotoko (Kumasi)
• 1992–93: Asante Kotoko (Kumasi)
• 1993–94: Goldfields (Obuasi)
• 1994–95: Goldfields (Obuasi)
• 1995–96: Goldfields (Obuasi)
• 1996–97: Hearts of Oak (Accra)
• 1997–98: Hearts of Oak (Accra)
• 1999: Hearts of Oak (Accra)
• 2000: Hearts of Oak (Accra)
• 2001: Hearts of Oak (Accra)
• 2002: Hearts of Oak (Accra)
• 2003: Asante Kotoko (Kumasi)
• 2004–05: Hearts of Oak (Accra)
• 2005: Asante Kotoko (Kumasi)
• 2006–07: Hearts of Oak (Accra)
• 2007–08: Asante Kotoko (Kumasi)
• 2008–09: Hearts of Oak (Accra)
• 2009–10: Aduana Stars (Dormaa)
• 2010–11: Berekum Chelsea (Berekum)
• 2011–12: Asante Kotoko (Kumasi)
• 2012–13: Asante Kotoko (Kumasi)
• 2013–14: Asante Kotoko (Kumasi)
• 2015: Ashanti Gold (Obuasi)
• 2016: Wa All Stars (Wa)
• 2017: Aduana Stars (Dormaa)
• 2018: abandoned
• 2019: GFA Normalization Committee Special Competition: Asante Kotoko (Kumasi)
• 2019–20: Cancelled
• 2020–21: Hearts of Oak (Accra)